Gene Synthesis Market Size, Share, Demand and Forecast 2025-2033

The global gene synthesis market size was valued at USD 2.41 Billion in 2024. Looking forward, IMARC Group estimates the market to reach USD 9.60 Billion by 2033, exhibiting a CAGR of 15.75% from 2025

Global Gene Synthesis Industry: Key Statistics and Insights in 2025-2033

Summary:

• The global gene synthesis market size reached USD 2.4 Billion in 2024.

• The market is expected to reach USD 9.6 Billion by 2033, exhibiting a growth rate (CAGR) of 15.75% during 2025-2033.

• North America leads the market, accounting for the largest gene synthesis market share.

• Solid-phase synthesis accounts for the majority of the market share in the method segment due to its high efficiency and scalability, allowing for rapid, accurate production of complex gene sequences.

• Antibody DNA synthesis holds the largest share in the gene synthesis industry.

• Gene and cell therapy development represents the leading application segment.

• Academic and government research institutes remain a dominant segment in the market.

• The increasing use of gene synthesis in research, drug discovery, and biotechnology is a primary driver of the gene synthesis market.

• The rise of clustered, regularly interspaced short palindromic repeats (CRISPR) and other gene-editing technologies is e reshaping the gene synthesis market.

Industry Trends and Drivers:

• Expanding Applications in Research and Biotechnology:

The demand for gene synthesis is growing. This trend is evident in drug development and biotechnology. Scientists use gene synthesis to create precise genetic material. This aids research on diseases and the design of genetic therapies. It also allows for the creation of genetically modified organisms. The ability to customize speeds up research. Scientists can now study molecular processes directly. Previously, they relied on DNA isolation, which was slower. In biotechnology, gene synthesis produces enzymes and proteins. It also creates bioengineered products on an industrial scale. These applications are crucial for biofuels, pharmaceuticals, and agriculture. As a result, synthetic gene services are increasing. Laboratories and biotech firms are investing more in these areas. Technological advances are also reducing costs and improving accuracy.

• Advancements in CRISPR and Gene Editing Technologies:

CRISPR and other gene editing technologies rely heavily on synthetic genes. These genes are essential reagents in the editing process. Companies that specialize in gene synthesis provide oligonucleotides. These carefully designed sequences act as substrates for CRISPR modifications. This support makes genome editing projects easier. They can now be done with unmatched precision and at larger scales. Previously, such achievements were nearly impossible. The application of CRISPR is expanding. It now includes not just correcting genetic diseases but also improving agricultural traits. Synthetic genes play a crucial role in this broader spectrum. They are used for both experiments and ensuring reproducibility in studies. The market growth is driven by the combined use of gene synthesis and gene editing technologies.

• Growing Demand for Personalized Medicine and Synthetic Biology:

Personalized medicine and synthetic biology are transforming healthcare. They both increase the need for gene synthesis. Personalized medicine tailors treatments to genetic profiles. Creating specific genes or DNA is often required for this. On the other hand, synthetic biology designs organisms for particular tasks. For instance, some bacteria are engineered to break down pollutants or produce biofuels. Here, gene synthesis is vital. It enables the creation of precise DNA necessary for these projects. As interest in these fields grows, so does the demand for flexible and accurate gene synthesis. This trend drives providers to enhance their methods.

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Gene Synthesis Market Report Segmentation:

Breakup By Method:

• Solid-Phase Synthesis

• Chip-Based Synthesis

• PCR-Based Enzyme Synthesis

Solid-phase synthesis represents the largest segment due to its high efficiency and scalability, allowing for rapid, accurate production of complex gene sequences.

Breakup By Services:

• Antibody DNA Synthesis

• Viral DNA Synthesis

• Others

Antibody DNA synthesis holds the biggest market share because of the growing need for custom antibodies in medical research, diagnostics, and therapeutic development.

Breakup By Application:

• Gene and Cell Therapy Development

• Vaccine Development

• Disease Diagnosis

• Others

Gene and cell therapy development account for the majority of the market share, driven by the increasing focus on genetic treatments for complex diseases.

Breakup By End Use:

• Biotechnology and Pharmaceutical Companies

• Academic and Government Research Institutes

• Contract Research Organizations

Academic and government research institutes represent the leading segment as they drive foundational research and development across various gene synthesis applications.

Breakup By Region:

• North America (United States, Canada)

• Asia Pacific (China, Japan, India, South Korea, Australia, Indonesia, Others)

• Europe (Germany, France, United Kingdom, Italy, Spain, Russia, Others)

• Latin America (Brazil, Mexico, Others)

• Middle East and Africa

North America enjoys the leading position attributed to its extensive government funding, advanced biotechnology infrastructure, and a strong focus on healthcare innovation.

Top Gene Synthesis Market Leaders:

The gene synthesis market research report outlines a detailed analysis of the competitive landscape, offering in-depth profiles of major companies. Some of the key players in the market are:

• ATUM

• Boster Biological Technology

• Eurofins Genomics

• Genewiz Inc. (Azenta Life Sciences)

• Genscript Biotech Corp.

• Integrated DNA Technologies Inc.

• Merck KGaA

• OriGene Technologies Inc.

• ProMab Biotechnologies Inc.

• ProteoGenix Inc

• Thermo Fisher Scientific Inc.

• Twist Bioscience

Note: If you require any specific information that is not covered currently within the scope of the report, we will provide the same as a part of the customization.

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